HISTAMINE RECEPTORS IN THE NEWBORN'S PULMONARY CIRCULATION
نویسندگان
چکیده
منابع مشابه
Histamine and H1-histamine receptors faster venous circulation
The study has analysed the action of histamine in the rabbit venous system and evaluated its potential role in contraction during increased venous pressure. We have found that a great variety exists in histamine sensitivity and H(1) -histamine receptor expression in various types of rabbit veins. Veins of the extremities (saphenous vein, femoral vein, axillary vein) and abdomen (common iliac ve...
متن کاملThe Effect of Histamine on the Pulmonary Circulation in Man ¶
The influence of intra-alveolar pressure and respiratory mechanics on pulmonary hemodynamics has been extensively studied.' Rodbard has presented the view that bronchomotor tone is a prominent factor in the regulation of pulmonary blood flow,' but the effect of bronchoconstriction on pulmonary pressure and flow has, so far, been studied very little in humans.' If the pulmonary hypertension obse...
متن کاملEffect of histamine on the pulmonary circulation in dogs.
Histamine was administered to dogs by the intravenous route near the right atrium in doses of 9.6 to 19 y/Kg. body weight. It produced a severe drop in systemic blood pressure, negligible changes in heart rate and respiration, usually a fall in cardiac output and no change in left atrial or pulmonary artery wedge pressure. The pulmonary artery pressure showed an initial rise and then a fall fol...
متن کاملHistamine receptors in the coronary circulation of the dog. Effects of mepyramine and metiamide on responses to histamine infusions.
The effect of histamine on coronary blood flow (CBF) was studied in anaesthetized grayhounds. CBF and systemic blood pressure were measured using electromagnetic flow transducers and catheters in the aorta during infusions of drugs into the left circumflex coronary artery. Histamine infusions (5, 10, and 20 microng/min) produced dose-related increases in CBF without changing heart rate or bloo...
متن کاملAdrenergic mechanisms in the effects of histamine in the pulmonary circulation of the cat.
Histamine constricts airways and pulmonary blood vessels in isolated lungs, but is said to dilate pulmonary blood vessels in intact animals. The present experiments test the hypodiesis that histamine only constricts pulmonary blood vessels, and that dilatation depends on epinephrine released by histamine from die adrenal glands. In cats anesthetized with pentobarbital, the difference in pressur...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1977
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197704000-01209